Risk Factors for the Development of Hyaline Membrane Disease in Preterm Infants

.ABSTRACT Hyaline membrane disease (HMO) is 1 r spunto1y liseasc c.:omm nly found in pr tern infants. Whil th1s disease occurs as th result ol surfa WJ1t ddi. icnc , which is a function of gestali nal age, certain maternal and neonatal factors play a role m the development of the d1sorder. Preterm mfants born al Lh D parlment f ( bst •trics and Gynecology, Cipto Mangunkusumo Hospital, Jakarta, between, March 1997 and May 1998 were studied for the development of HMO. It was concluded that antepartum hemorrhage, gestational ag , sex, mod of birth, and the lirst minute Apgar score were associated with the development of HMD, whit· the use of ontraccpt.lv s, early rupture of the membrane, maternal morbidity, and passive cigat tte smoking were not. [Paediatr Indones 1998; 38:243-254].